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应用经腺病毒介导释放的单纯疱疾病毒胸苷激酶（HSV－TK）基因作为胰腺癌基因洽疗的工具。选用人体胰腺癌细胞系B×PC－3、ASPC－1、HPAF和Panc－1，注入Balb／C裸鼠腹腔内制成胰腺癌模型。HSV－TK表达能致敏细胞至核着同类物ganciclovir（GCV），后者是抗病毒剂。选择性致敬可
Application of adenovirus-mediated release of the simple thymidine kinase (HSV-TK) gene as a pancreatic cancer gene therapy tool. Human pancreatic cancer cell lines B×PC-3, ASPC-1, HPAF and Panc-1 were injected into the abdominal cavity of Balb/C nude mice to make a pancreatic cancer model. HSV-TK expresses sensitized cells to the nuclear homolog ganciclovir (GCV), which is an antiviral agent. Selective salutation