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[目的]评价致康胶囊在反流性食管炎(RE)治疗中的疗效。[方法]100例患者按入组先后分为2组,每组各50例。其中,A组给予耐信+莫沙必利+致康胶囊治疗,B组给予耐信+莫沙必利治疗。治疗8周后分别比较2组患者的临床症状及内镜下RE的变化情况。[结果]治疗后A组临床症状显效42例,有效6例,无效2例;B组显效38例,有效7例,无效5例,A组稍优于B组,但差异无统计学意义。内镜下RE恢复情况A组显效38例,有效10例,无效2例;B组显效26例,有效18例,无效6例,A组明显优于B组,差异有统计学意义(P<0.05)。[结论]致康胶囊能促进RE的愈合,并可能有助于改善RE的临床症状。
[Objective] To evaluate the efficacy of Zhikang capsule in the treatment of reflux esophagitis (RE). [Methods] 100 patients were divided into two groups according to the group, each group of 50 cases. Among them, A group was given the letter of resistance + mosapride + Zhikang capsule treatment, B group was given letter + mosapride treatment. After 8 weeks of treatment, the clinical symptoms and changes of RE under endoscopy were compared between the two groups. [Results] After treatment, the clinical symptoms of group A were significantly improved in 42 cases, effective in 6 cases and ineffective in 2 cases. In group B, 38 cases were markedly effective, 7 cases were effective and 5 cases were ineffective. The difference between groups A and B was not significant. There were 38 cases in group A, 10 cases were effective in 2 cases, 2 cases were ineffective in group A, 26 cases were effective in group B, 18 cases were effective and 6 cases were ineffective in group A. The difference between group A and group B was statistically significant (P < 0.05). [Conclusion] Zhikang capsule can promote the healing of RE and may help to improve the clinical symptoms of RE.