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目的探讨美沙拉秦栓治疗溃疡性结肠炎的疗效。方法将溃疡性结肠炎患者75例随机分为两组,治疗组采用美沙拉秦栓治疗,与对照组采用双料喉风散灌肠进行对比,疗程2～3周,疗程结束后行结肠镜检查,并随访1 a。结果治疗组近期治愈率为41.5%,总有效率为96.9%,对照组分别为19.1%和81.0%。两组近期治愈率和总有效率差异有统计学意义(P<0.05,P<0.01)。治疗后观察各项指标,治疗组明显优于对照组及治疗前(P<0.05)。结论美沙拉秦栓治疗溃疡性结肠炎是一种有效的方法。
Objective To investigate the efficacy of mesalamine suppository in the treatment of ulcerative colitis. Methods 75 patients with ulcerative colitis were randomly divided into two groups. The treatment group was treated with mesalamine suppository, compared with the control group with double throat wind scattered enema for 2 to 3 weeks. After the treatment, colonoscopy was performed, Follow-up 1 a. Results The cure rate of the treatment group was 41.5%, the total effective rate was 96.9%, the control group were 19.1% and 81.0%. The two groups of recent cure rate and total effective rate difference was statistically significant (P <0.05, P <0.01). After treatment, the indexes were observed, the treatment group was significantly better than the control group and before treatment (P <0.05). Conclusion Mesalazine suppository is an effective method for treating ulcerative colitis.