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目的探讨急性脑梗死、短暂性脑缺血发作和急性脑出血患者血清学指标的特点。方法急性脑梗死患者63例,急性脑出血患者62例,短暂性脑缺血发作患者35例,比较三组患者纤维蛋白原、同型半胱氨酸的不同。结果急性脑梗死患者血清纤维蛋白原显著低于急性脑出血组(P<0.001),同型半胱氨酸水平高于急性脑出血组(P<0.05),但与短暂性脑缺血发作组均无统计学差异。短暂性脑缺血发作组患者血清纤维蛋白原显著低于急性脑出血组(P<0.001),同型半胱氨酸水平与急性脑出血组无差异(P>0.05)。结论纤维蛋白原和同型半胱氨酸与急性脑血管病的发生可能有关,定期化验,及早干预,可能会降低脑血管病的发病率。
Objective To investigate the characteristics of serum markers in patients with acute cerebral infarction, transient ischemic attack and acute cerebral hemorrhage. Methods Sixty-three patients with acute cerebral infarction, 62 patients with acute cerebral hemorrhage and 35 patients with transient ischemic attack were included in this study. The differences of fibrinogen and homocysteine between the three groups were compared. Results Serum fibrinogen in patients with acute cerebral infarction was significantly lower than that in acute intracerebral hemorrhage (P <0.001) and homocysteine levels were higher in patients with acute cerebral hemorrhage (P <0.05) No statistical difference. The level of serum fibrinogen in patients with transient ischemic attack was significantly lower than that in patients with acute intracerebral hemorrhage (P <0.001). There was no difference in the level of homocysteine between acute cerebral hemorrhage and acute cerebral hemorrhage (P> 0.05). Conclusion Fibrinogen and homocysteine may be related to the occurrence of acute cerebrovascular disease. Regular tests and early intervention may reduce the incidence of cerebrovascular disease.