论文部分内容阅读
目的研究γ亚麻油酸对机体血脂的调节作用。方法利用口服高脂饲料所致大鼠及家兔实验性高脂血症模型。结果γ亚麻油酸预防性给药，可显著降低大鼠血清ＴＧ，ＴＣＨ，ＬＤＬｃｈ及ＶＬＤＬｃｈ含量；对家兔血清ＴＣＨ，ＬＤＬｃｈ及ＶＬＤＬｃｈ含量也有显著降低作用，但对ＴＧ水平无明显影响；γ亚麻油酸治疗性给药，对家兔血脂中，ＴＧ，ＴＣＨ，ＬＤＬｃｈ及ＶＬＤＬｃｈ含量有显著降低作用，对心肌组织中ＴＧ和ＴＣＨ含量也有明显降低，并可显著降低家兔全血粘度低切变率。结论γ亚麻油酸具有显著调节高脂血症模型大鼠及家兔血脂的作用，延缓组织血脂沉积，并可有效降低血液粘度。
Objective To study the regulation effect of γlinolenic acid on blood lipids. Methods The experimental hyperlipidemia model was induced in rats and rabbits by oral administration of high-fat diet. Results γlinolenic acid prophylaxis administration can significantly reduce the rat serum TG, TCH, LDL ch and VLDL content; rabbit serum TCH, LDL ch and VLDL ch were also significantly reduced, but The TG level had no significant effect; γ linoleic acid therapeutic administration of rabbit blood lipids, TG, TCH, LDL ch and VLDL ch were significantly reduced the content of myocardial TG and TCH also significantly Reduce, and can significantly reduce the rabbit whole blood viscosity low shear rate. Conclusion γlinolenic acid can significantly regulate hyperlipemia model rats and rabbits blood lipids, delay tissue lipid deposition, and can effectively reduce the blood viscosity.