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2005年以来,美国免疫实施咨询委员会(Advisory Committeeon Immunization Practices,ACIP)一直推荐11～18岁青少年(优先在11～12岁)和从未接种过破伤风类毒素、降低抗原含量的白喉类毒素、无细胞百日咳(百白破)联合疫苗[Tetanus Toxoid(TT),Reduced Diphtheria Toxoid(dT)and Acellular Pertussis(aP)Combined Vaccine;Tdap]的19～64岁成人加强接种1剂Tdap。2010年10月,虽然缺少批准上市用于≥65岁成人接种的Tdap,但ACIP仍建议
Since 2005, the Advisory Committee on Immunization Practices (ACIP) has been recommending diphtheria toxoid in adolescents aged 11 to 18 years (preferentially aged 11 to 12 years) and those who have never been vaccinated with tetanus toxoid to reduce antigen levels, A 19-year-old, 64-year-old adult with acellular pertussis (TDP) combination vaccine [Tetanus Toxoid (TT), Reduced Diphtheria Toxoid (dT) and Acellular Pertussis (aP) Combined Vaccine; Tdap] was boosted with 1 dose of Tdap. In October 2010, despite the lack of a Tdap approved for marketing for adults ≥65 years of age, ACIP still recommends