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目的分析福建省6个监测点急性乙肝报告的病例资料,评价其实际发病情况。方法对报告的急性病例进行流行病学调查,采集血清进行实验室复核。结果 2013年共报告乙肝4 086例,初始报告急性乙肝692例(16.9%)、慢性乙肝3 373例(82.7%)、未分类21例(0.5%)。经流行病学调查及抗-HBc-IgM 1∶1000检测排除,审核订正后报告急性乙肝269例(6.6%),慢性乙肝3 796例(92.9%),订正后急性乙肝病例占比下降;乙肝发病性别比2.1∶1。抗HBc-IgM估算的急性乙肝发病率明显低于中国疾病预防控制系统报告发病率。结论应提高医务人员对乙肝诊断标准的认识,及时利用实验室检测结果进行乙肝分类诊断,客观评价福建省乙肝发病水平。
Objective To analyze the case information of acute hepatitis B reported from 6 monitoring points in Fujian Province and evaluate its actual incidence. Methods The reported acute cases were investigated by epidemiology, and serum was collected for laboratory review. Results A total of 4 086 cases of hepatitis B were reported in 2013, of which 692 (16.9%) were acute hepatitis B, 3 373 (82.7%) were chronic hepatitis B and 21 (0.5%) were not classified. According to epidemiological investigation and anti-HBc-IgM 1: 1000 test, 269 cases (6.6%) of acute hepatitis B and 3 796 (92.9%) cases of chronic hepatitis B were reported after revision. The proportion of acute hepatitis B The incidence of sex ratio 2.1: 1. The incidence of acute hepatitis B as estimated by anti-HBc-IgM was significantly lower than the reported incidence of disease control in China. Conclusion The medical staff should raise the awareness of diagnostic criteria of hepatitis B, diagnose the diagnosis of hepatitis B in time and make objective evaluation of the incidence of hepatitis B in Fujian Province.