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目的了解昭通市急性出血性结膜炎(简称AHC)流行的原因。方法用描述流行病学方法对AHC流行时的个案调查资料进行分析,采集部分AHC病人眼拭子样品,进行病毒分离。结果2007年1～12月共发病3 843例,发病高峰在8～9月。发病率平均为72.69/10万,病人通过直接或间接触传播,病例有高度聚集性,发病以学生为主,占发病总数的43.60%;其次是农民,占37.00%。从采集的30份眼拭子样品中分离柯萨奇病毒A24变种11株。结论昭通市AHC流行是由柯萨奇病毒A24变异株引起,今后要加强疫情监测及健康教育力度,尤其是学生、农民AHC卫生知识宣传,防止疫情再次暴发。
Objective To understand the causes of the epidemic of acute hemorrhagic conjunctivitis (referred to as AHC) in Zhaotong. Methods Descriptive epidemiological method was used to analyze the case-finding data of AHC prevalence. Some eye-swab samples from AHC patients were collected for virus isolation. Results From January to December 2007, a total of 3 843 cases were reported, with the peak incidence from August to September. The average incidence was 72.69 / 100 000. The patients were spread by direct or indirect contact. The cases were highly aggregated. The incidence was student-centered, accounting for 43.60% of the total number of cases. The second was farmers, accounting for 37.00%. Eleven strains of Coxsackievirus A24 variants were isolated from 30 eye-swab samples collected. Conclusion The prevalence of AHC in Zhaotong City was caused by the Coxsackievirus A24 mutant strain. In the future, it is necessary to strengthen the surveillance and education of epidemic situation, especially the propaganda of hygiene knowledge of AHC students and peasants to prevent the recurrence of the outbreak.