论文部分内容阅读
分析６０例原发性肾病综合征临床特点、病理改变、疗效和预后。其中５８例行肾活检，结果以系膜增生性肾炎和ＩｇＡ肾病最常见，分别占５１．７％和１７．２％。病理类型复杂多样，因此肾活检十分重要，可藉以明确诊断和选择治疗方案。治疗尽量个体化，对病理类型较重、蛋白尿＞３．５ｇ／ｄ者用冲击治疗。注意防止皮质激素和细胞毒药物的副作用。随访半～２年，总缓解率６７％，死亡９例（１７．２％），主要死因为肺部感染。
Analysis of 60 cases of primary nephrotic syndrome clinical features, pathological changes, efficacy and prognosis. Among them, 58 patients underwent renal biopsy, the most common cause was mesangial proliferative glomerulonephritis and IgA nephropathy, accounting for 51.7% and 17.2% respectively. Complex and diverse pathological types, so renal biopsy is very important, can be a clear diagnosis and selection of treatment options. Treatment as individualized, heavier pathological types, proteinuria> 3.5g / d with impact treatment. Pay attention to prevent side effects of corticosteroids and cytotoxic drugs. The follow-up of half to two years, the overall response rate was 67%, 9 patients died (17.2%), the main cause of death was pulmonary infection.