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目的::观察重症脑卒中患者肠内营养混悬液营养干预的疗效。方法:823例重症脑卒中患者按就诊顺序分为两组。观察组423例患者采用肠内营养混悬液进行鼻饲,对照组400例患者采用家庭自制匀浆膳食进行鼻饲。两组患者均根据疾病类型选择合适的常规处理措施进行治疗。比较两组患者治疗前后的血总蛋白( TB)、血红蛋白( Hb)、血白蛋白( Alb)、三酰甘油( TG)等营养指标,以及神经功能缺损评分( NIHSS)、Barthel指数,肌力恢复状况及治疗后的并发症。结果:两组患者的TB、Hb、Alb及TG等各项营养指标均显著下降(P<0.05),但观察组各项指标明显高于对照组(P<0.05)。两组患者的NIHSS评分均明显降低(P<0.01),Barthel指数明显升高(P<0.01);但观察组患者治疗后NIHSS评分与Barthel指数均明显优于对照组(P<0.05)。观察组肌力恢复明显高于对照组(P0.05)。结论:肠内营养混悬液能够有效改善重症脑卒中患者的营养状况,并发症少,安全性高,值得临床推广应用。“,”Objective:To observe the efficacy of enteral nutritional suspensions in the patients with severe stroke. Methods:To-tally 823 cases of severe stroke patients were divided into the observation group and the control group according to the visiting se-quence. The 423 cases in the observation group were treated with enteral nutritional suspensions, while another 400 patients in the con-trol group were given the home-made meals with nasal feeding, and relative routine treatment was given the patients according to the disease type in the two groups. Before and after the treatment, serum total protein ( TB) , hemoglobin ( HB) , serum albumin ( ALB) and TG of the two groups were recorded, neurological deficit scores ( NIHSS) , Barthel index, muscle recovery and complications were also studied and compared. Results:After the treatment, TB, HB, ALB and TG of the two groups were significantly decreased ( P<0. 05), while the nutritional indicators in the observation group were significantly higher than those in the control group (P<0. 05). After the treatment, NIHSS score of the two groups was significantly decreased (P<0. 01), Barthel index was significantly increased (P<0. 01), and those in the observation group were better than those in the control group (P<0. 05). The muscle recovery of the observation group was significantly higher than that of the control group (P0. 05). Conclusion: Enteral nutritional suspensions can improve the nutritional status of the pa-tients with severe stroke with fewer complications and better safety, which are worthy of clinical application.