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在很多皮肤粘膜病中,如多形红斑、Dühring—Brocq病(疱疹样皮炎)、大疱性类天疱疮、良性类天疱疮、大疱性苔癣及毒皮病等都可能发生口腔粘膜上皮下的水疱大疱性损害。天疱疮在这些水疱大疱性损害中占有重要的位置,不但口腔损害常见,而且又比皮肤更早出现,由于预后严重,故早期诊断非常必要。在口腔粘膜部位的水疱,因食物创伤的关系,疱易破裂,很快失去疱顶,并导致临床诊断为糜烂性的病变。随之而来的炎症变化,改变了组织学所见,造成组织病理学诊断的困难。
In many mucocutaneous diseases, such as erythema multiforme, Dühring-Brocq disease (dermatitis herpetiformis), bullous pemphigoid, benign pemphigoid, bullous lichen planus and toxic skin disease may occur oral Mucosal epidermal bullous bullous lesions. Pemphigus occupies an important position in these bullous bullous lesions, not only common oral lesions, but also earlier than the skin, early diagnosis is necessary due to the serious prognosis. Blisters in the oral mucosa, because of the relationship between food trauma, blisters easily rupture, soon lost blister top, and lead to clinical diagnosis of erosive lesions. The consequent changes in inflammation have changed the histological findings, resulting in the difficulty of histopathological diagnosis.