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１０４例晚期癌痛病人，Ｌ２～３或Ｌ３～４硬膜外间隙置管并连接全封闭硬膜外注射（ＣＣＥＩ）装置，注射０．０１％吗啡１０～１５ｍｌ，２～３次ｄ，去炎松Ａ４０ｍｇｄ，应用ＣＣＥＩ５０．０±４６．８（５～３５１）天未发现硬膜外腔感染，日均注射吗啡３．８４±３．９４ｍｇ和２．９９±１．１７次，不良反应率为７．６９％，ＣＣＥＩ吗啡初始量３．５５±２．５２ｍｇｄ，对照死亡前量３．４９±１．６３ｍｇｄ无显著差异（Ｐ＞０．０５）。死亡前平均视觉模拟评分３．１６±２．８３分，对照治疗前９．７８±０．９２分差异显著（Ｐ＜０．０５）。吗啡去炎松长期ＣＣＥＩ具有良好解除疼痛和防止硬膜外腔感染功能，同时也减少病人吗啡用量和不良反应。
One hundred and twenty-four patients with advanced cancer pain were placed in L2 ~ 3 or L3 ~ 4 epidural space and connected with CCEI. They were injected with 10-15ml 0.01% morphine and 2 ~ 3 times d, To the A40mg d, application of CCEI50.0 ± 46.8 (5 ~ 351) Days did not find epidural infection, average daily morphine injection 3.84 ± 3.94mg and 2.99 ± 1.17 times, The adverse reaction rate was 7.69%, the initial amount of morphine in CCEI was 3.55 ± 2.52 mg d, but there was no significant difference in the amount of 3.49 ± 1.63 mg before the control (P> 0.05). The average visual analogue score before death was 3.16 ± 2.83 points, and the difference was significant (P <0.05) 9.78 ± 0.92 points before treatment. Morphine triamcinolone long-term CCEI has a good pain relief and prevent epidural infection, but also reduce the patient’s morphine dosage and adverse reactions.