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目的:探讨选择性动脉化疗药物灌注及栓塞治疗结直肠癌肝转移的价值。材料与方法:对27例失去手术机会的结直肠癌肝转移患者,采用经股动脉穿刺,选择性肝动脉插管灌注化疗药物(ADM,CBP,FUDR),并用ADM及碘化油乳化后栓塞肝动脉。结果:在第1疗程结束后,19例患者肝内肿瘤有缩小,25例CEA降低,23例上腹疼痛减轻或消失。1、2、3年生存率分别是70.4%、51.9%、22.2%。结论:经肝动脉化疗药物灌注及栓塞治疗是失去手术机会的结直肠癌肝转移患者的一种安全、有效的姑息性治疗方法。
Objective: To investigate the value of selective arterial chemotherapy infusion and embolization in the treatment of colorectal cancer liver metastasis. MATERIALS AND METHODS: Twenty-seven patients with metastatic colorectal cancer liver metastases who lost their chances of surgery were treated with transcatheter arterial chemoembolization (ADM, CBP, FUDR) through selective femoral artery catheterization, and embolization with ADM and lipiodol Hepatic artery. Results: After the end of the first course of treatment, 19 patients had a reduction of intrahepatic tumors, 25 CEA decreased, and 23 patients with upper abdominal pain relieved or disappeared. The 1, 2, 3 year survival rates were 70.4%, 51.9% and 22.2% respectively. Conclusion: Perfusion and embolization of transcatheter arterial chemoembolization is a safe and effective palliative treatment for patients with liver metastasis of colorectal cancer who have lost their chance of operation.