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我们试用100mW～100mW低功率Nd:YAG激光分别在离体和活体动物内照射凝堵输精管。在离体标本测定不同激光功率和照射时间所致的阈损(伤设定1/2输精管管壁被穿透)及输精管外膜温度。在活体内,通过套管针插入直径200μm光导纤维对8只(16侧输精管)家兔行输精管腔内照射。功率800mW和1000mW,照射时间相应为24″和16″,术后3～4周输精管管腔完全闭塞。作者认为今后可望采用经皮输精管穿刺插入光导纤维腔内照射作为绝育手术,唯尚需更多实验研究以便应用于临床。
We try 100mW ~ 100mW low-power Nd: YAG laser coagulation of vasectomy in vitro and in vivo animals respectively. In vitro specimens were determined by different laser power and irradiation time caused by the threshold damage (injury set 1/2 of the seminiferous duct wall is penetrated) and the outer tube of the vas deferens temperature. In vivo, eight (16-sided vas deferens) rabbits received endovascular irradiation of the vas deferens by inserting a diameter of 200 μm optical fiber through a trocar. Power 800mW and 1000mW, irradiation time corresponding to 24 “and 16”, 3 to 4 weeks after the vas deferens completely occluded. The author believes that the future is expected to use percutaneous vas deferens inserted into the optical fiber cavity as a sterilization surgery, but still need more experimental study for clinical application.