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1978年观察1例注射狂犬病疫苗所引起的脑膜脑炎型患者,现简要报告如下。患者,男性,14岁,学生,住院号13848。因发热、头痛、四肢抽搐,于1978年7月18日来本院就诊。病史:患者17天前右大腿被狗咬伤,伤部少量出血,当时无头痛、头晕、发热症状,伤口未经处理自愈。5天后开始注射狂犬病疫苗(按常规剂量疗程),注射至第11天后感觉头痛发热,合作医疗室按感冒处理。次日晚11时,头痛加剧伴四肢抽搐,声音嘶哑,流口水,不能语言,遂于下半夜转送我院。早晨8时四肢又抽搐,神志仍然不清。体检:T36.5℃(腋下),P78次/分,R21次/分,BP100/70mmHg,神志昏迷,瞳孔对光反射存在,颈部对抗,双侧Babinski、Oppenheim、Gordon氏征均阳性。脑脊液常规:无色稍混,呈碱性,潘氏试验阳性,糖75mg％,
In 1978, one case of meningoencephalitis caused by rabies vaccine injection was briefly reported as follows. Patient, male, 14 years old, student, hospital number 13848. Due to fever, headache, limbs twitch, in July 18, 1978 to our hospital. History: The patient had a bite of his right thigh 17 days earlier, a small amount of bleeding from the wound, and no headache, dizziness, fever and wound healing. Rabies vaccine is given 5 days later (at the usual dose), with headache and fever after injection on day 11, and colds in co-op room. 11 o’clock the next day, the headache aggravated with limbs twitch, hoarse voice, drooling, can not speak, then in the next night forwarded to our hospital. The limbs twitched again at 8 a.m., and the mind remained unclear. Physical examination: T36.5 ℃ (armpit), P78 beats / min, R21 beats / min, BP100 / 70mmHg, delirium, pupil light reflex, neck confrontation, bilateral Babinski, Oppenheim, Gordon’s sign were positive. Cerebrospinal fluid routine: colorless slightly mixed, alkaline, positive Pan’s test, sugar 75mg%