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目的观察新通管方联合选择性输卵管造影及输卵管再通术(SSG+FTR)对输卵管阻塞性不孕症的临床疗效和安全性。方法将169例输卵管阻塞性不孕症患者随机分为治疗组80例和对照组89例。治疗组给予SSG+FTR术和口服新通管方,新通管方每日1剂,分2次口服,每次200ml;对照组单纯行SSG+FTR手术。观察两组患者的宫内妊娠率、术后妊娠时间、早期流产率及异位妊娠率。结果治疗组宫内妊娠率明显优于对照组(P<0.05)。治疗组第1疗程及第3疗程宫内妊娠率明显高于对照组(P<0.05)。两组早期流产率及异位妊娠率差异无统计学意义(P<0.05)。治疗期间未见明显不良反应。结论新通管方联合SSG+FTR术后可提高输卵管阻塞性不孕症患者的宫内妊娠率,缩短妊娠时间,未见有明显不良反应。
Objective To observe the clinical effect and safety of Xintong pipet combined with selective salpingography and tubal recanalization (SSG + FTR) on tubal obstruction infertility. Methods A total of 169 patients with tubal obstruction infertility were randomly divided into treatment group (n = 80) and control group (n = 89). The treatment group was given SSG + FTR surgery and oral administration of new Tong Guan, Xin Tong tube side 1 day, 2 times orally, each 200ml; control group simple line SSG + FTR surgery. Intrauterine pregnancy rate, postoperative pregnancy time, early miscarriage rate and ectopic pregnancy rate were observed in two groups of patients. Results The treatment group intrauterine pregnancy rate was significantly better than the control group (P <0.05). The intrauterine pregnancy rate of the first course and the third course of the treatment group was significantly higher than that of the control group (P <0.05). There was no significant difference in early abortion rate and ectopic pregnancy between the two groups (P <0.05). No significant adverse reactions during treatment. Conclusions New Tong Guan combined with SSG + FTR can improve the intrauterine pregnancy rate and shorten the pregnancy time in patients with tubal obstruction infertility and no obvious adverse reactions.