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睾丸原发性非霍奇金淋巴瘤临床上较少见。该肿瘤术前诊断困难,需手术病理证实。我院近年来收治2例,现报告如下: 例1 男,65岁,左侧睾丸无痛性进行性肿大2月余,于1995年9月28日入院。查体:一般情况好,全身浅表淋巴结未触及,心、肺、肝、脾未查到异常,腹部未及肿块,左侧睾丸9.0cm×5.0cm×4.0cm,表面光滑、质硬、无触痛,右侧睾丸无异常。腹部MRI未见有腹主动脉旁淋巴结肿大。术中见左睾丸肿大伴鞘膜积液,与阴囊壁无粘连,于左内环口处切除左侧精索、附睾及睾丸。术后病理示高度恶性B细胞型恶性淋巴瘤,累及精索。免疫组化结果:LCA(+)、L-26(+)、UCHL-1(-)、PLAP(-)。术后2周行CHOP方案化疗5个疗程、COEDP方案2个疗程。随访8个月、病情稳定,目前仍在随访中。
Testicular primary non-Hodgkin’s lymphoma is rare in clinical practice. The preoperative diagnosis of this tumor is difficult, requiring pathological confirmation. Our hospital has treated 2 cases in recent years, and the report is as follows: Example 1 Male, 65 years old, painless progressive swelling of the left testis more than 2 months, was admitted to hospital on September 28, 1995. Physical examination: In general, the whole body has no palpable lymph nodes, no abnormalities are found in the heart, lungs, liver and spleen, and there are no abdominal masses. The left testis is 9.0cm×5.0cm×4.0cm. The surface is smooth, hard and non-existent. Tenderness, no abnormality of the right testis. Abdominal MRI showed no abdominal aortic lymphadenectasis. During the operation, the left testicle was swollen with hydrocele, and there was no adhesion with the scrotum wall. The left spermatic cord, epididymis and testis were removed at the left inner ring. Postoperative pathology showed highly malignant B-cell malignant lymphoma with involvement of spermatic cords. Immunohistochemistry results: LCA(+), L-26(+), UCHL-1(-), PLAP(-). Two weeks after operation, 5 courses of CHOP regimen and 2 courses of COEDP regimen were performed. Followed up for 8 months, the condition was stable, and it is still being followed up.