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目的了解高校教师血尿酸(UA)水平其及相关危险因素,为高校教职工慢性病防治提供参考。方法以云南大学2011年5月至2012年10月接受健康体检的2 947名教职工为研究对象,分别测定其身高、体重、血压、血脂、血糖,分析血尿酸(UA)水平、分布特征及UA和高尿酸血症(HUA)的危险因素。结果体检教师HUA患病率为12.4%,男性为16.6%,女性为5.7%。不同性别、年龄、体质量指数教师UA水平、HUA患病率差异有统计学意义(P值均<0.01)。收缩压、体质量指数、空腹血糖、三酰甘油、高密度脂蛋白胆固醇是尿酸水平的危险因素,而HDL-C是女性的保护因素(P值均<0.01)。高龄、超重、血压高、高三酰甘油、高低密度脂蛋白胆固醇、低高密度脂蛋白胆固醇是HUA的危险因素(P值均<0.05)。结论高校教师血尿酸水平随年龄和体质量指数的增长而增高。应加大对超重肥胖男性及绝经后女性教师的干预力度。
Objective To understand the level of serum uric acid (UA) and its related risk factors in colleges and universities, and provide references for the prevention and treatment of chronic diseases among college faculty. Methods A total of 2 947 faculty members from Yunnan University from May 2011 to October 2012 were enrolled in this study. Their height, weight, blood pressure, blood lipids, blood glucose, blood uric acid (UA) UA and hyperuricemia (HUA) risk factors. Results The prevalence of HUA in physical examination teachers was 12.4%, 16.6% in males and 5.7% in females. The gender, age, body mass index of teachers UA level, HUA prevalence difference was statistically significant (P all <0.01). Systolic blood pressure, body mass index, fasting blood glucose, triglyceride, and high-density lipoprotein cholesterol were risk factors for uric acid, whereas HDL-C was a protective factor for women (P <0.01). Elderly, overweight, high blood pressure, high triglyceride, high and low density lipoprotein cholesterol, and low-density lipoprotein cholesterol are risk factors for HUA (all P <0.05). Conclusion The level of serum uric acid in college teachers increased with age and body mass index. Should increase the overweight obese men and postmenopausal women teachers intervention.