Thrombospondin 1 promotes synaptic formation in bone marrow-derived neuron-like cells

• 作 者: Yun Huang Mingnan Lu Weitao Gu
• 机 构: DepartmentofOrthopedics
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2013年10期
• 关键词: 骨髓间质干细胞 神经元样细胞 突触形成 血小板 蛋白 反应 骨髓间充质干细胞 细胞形态 neural regeneration stem cells bone
• 基金项目: supported by the Natural Science Foundation of Guangdong Province, No. S2011010004096,the Medical Scientific Research Foundation of Guangdong Province, No. A2010431, A2009477

In this study, a combination of growth factors was used to induce bone marrow mesenchymal stem cells differentiation into neuron-like cells, in a broader attempt to observe the role of thrombospondin 1 in synapse formation. Results showed that there was n