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很多作者报告过在肾脏疾病过程中可发生肢体近端肌肉无力,在双侧肾切除并肾移植后肌无力有很大改善。本文作者报告一例儿童患Duchene氏型肌营养不良,以后又发生了肾脏疾病,需行双肾摘除并一侧肾移植,移植后的头几个月,肌病恶化,但以后即有明显进步,并保持了四年。作者等认为患儿患有原发性肌营养不良,而非继发于肾脏疾病的肌病。与过去该院住院病例对照,作者认为本例肌肉功能改善并非由于住院所行之物理治疗及肾移植后的药物治疗所致,而是由于一个健康肾脏的移植。移植的肾脏产生一种具有血管运动效应,部分地抵销微循环异常的物质,从而使其
Many authors have reported that proximal limb muscle weakness can occur during kidney disease and that there is a significant improvement in myasthenia gravis after bilateral nephrectomy and kidney transplantation. The authors of this report report a case of Duchene’s muscular dystrophy in children. Later, kidney disease occurred. Nephrectomy and bilateral kidney transplantation were required. In the first few months after transplantation, myopathy deteriorated, but significant improvements were made thereafter. And for four years. The authors believe that children with primary muscular dystrophy, rather than secondary to kidney disease myopathy. Compared with the past hospitalized cases in this hospital, the author thinks that the improvement of muscular function in this case is not due to the physical therapy in hospital and the drug treatment after kidney transplantation, but due to the transplantation of a healthy kidney. Transplanted kidneys produce a substance that has a vasomotor effect that partially counteracts the microcirculation anomaly so that it