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目的 :从组织病理学上对利用脱细胞的羊膜行脉络膜再血管化手术进行分析研究。方法 :利用脱细胞的羊膜组织对 8只兔眼的再血管化行手术治疗 ,分别于术后 10天、1、3、6个月摘除 2只兔的双眼 ,对其进行光镜和电镜检查。结果 :术后 1～ 6个月移植物与周围组织生长紧密 ,有较多新生血管长出 ,局部脉络膜血管扩张 ,血管周围可见异物巨细胞。结论 :利用脱细胞的羊膜组织脉络膜上腔植入行脉络膜再血管化是一种安全有效的治疗方法 ,其可以刺激新生血管生长、促进吞噬细胞聚集 ,改善视网膜和脉络膜的血供
OBJECTIVE: To study the histopathology of choroidal revascularization using acellular amniotic membrane. Methods: The revascularization of 8 rabbit eyes was performed with acellular amniotic tissue. The eyes of 2 rabbits were removed at 10 days, 1, 3, and 6 months after operation, and examined by light and electron microscopy . Results: The implants grew well with the surrounding tissue in 1 ~ 6 months after operation. There were more neovascularization, local choroidal vasodilation and foreign bodies giant cells in the periphery of blood vessels. CONCLUSION: Choroidal vascularization using acellular amniotic membrane choroidal vascularization is a safe and effective treatment, which can stimulate the growth of new blood vessels, promote the aggregation of phagocytes and improve the blood supply of the retina and choroid