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目的:探讨慢性鼻-鼻窦炎(CRS)病变程度与支气管哮喘肺功能的相关性。方法选择72例慢性鼻-鼻窦炎患者(研究组)和64例非慢性鼻-鼻窦炎患者(对照组),对患者行脉冲振荡法(IOS)及通气肺功能检查、慢性鼻-鼻窦炎调查问卷,分析CRS病变程度与支气管哮喘肺功能的相关性。结果① CRS合并支气管哮喘发生率较高,研究组与对照组相比FEV1、FEF25-75差异具有统计学意义(P<0.05);②研究组中CRS病变程度及范围与FEV1、FEF25-75下降有一定的相关性(P<0.05);③研究组中CRS病变程度与肺功能相关指标有一定相关性(P<0.05)。结论 CRS病变程度与支气管哮喘肺功能下降有一定的相关性。CRS合并支气管哮喘肺功能呈明显的下降趋势。“,”Objective To investigate the correlation of the severity of chronic nasal-rhinosinusitis (CRS)with asthma and bronchial pulmonary lung function.Methods A total of 72 patients with chronic nasal-sinusitis patients (the study group)and 64 patients with non-chronic rhino-sinusitis patients (the control group)were enrolled in this study.Impulse oscillation (IOS)and ventilatory pulmonary function were determined,and chronic rhino-sinusitis questionnaires were carried out.Results ①CRS bronchial asthma was higher in the study group,compared with the control group,FEV1 and FEF25-75 were statistically significant (P<0.05);②In the study group severity and extent of CRS had some corre-lation with decrease of FEV1 and FEF25-75 (P<0.05 );③ Severity of IOS had some relevance to lung function (P<0.05).Conclusion Severity of CRS has some relevance to asthma and bronchial pulmonary lung function.Patients with CRS and bronchopulmonary asthma have a significant decline in lung function.