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目的观察分析孟鲁司特佐治支气管哮喘患儿的临床疗效。方法选取48例支气管哮喘患儿为研究对象,随机分为治疗组(26例)和对照组(22例)。两组患儿均按支气管哮喘常规治疗,治疗组在此治疗基础上加服孟鲁司特,观察比较两组患儿的临床治疗效果。结果治疗组患儿显效23例(88.5%),有效2例(7.7%),无效1例(3.8%),治疗总有效率为96.2%;对照组患儿显效13例(59.1%),有效2例(9.1%),无效7例(31.8%),总有效率为68.2%;治疗组患儿治疗总有效率明显高于对照组,差异具有统计学意义(χ2=6.71,P<0.05)。两组在治疗前后检测血常规、尿常规及肝肾功能均无异常,未发现严重副作用。结论孟鲁司特钠联合布地奈德治疗儿童支气管哮喘,疗效显著,能很好的控制哮喘复发,减少患儿痛苦,值得临床推广。
Objective To observe and analyze the clinical efficacy of montelukast in children with bronchial asthma. Methods Forty-eight children with bronchial asthma were randomly divided into treatment group (n = 26) and control group (n = 22). The two groups of children were routinely treated with bronchial asthma. The treatment group was given montelukast on the basis of this treatment, and the clinical effects of the two groups were observed and compared. Results In the treatment group, 23 cases (88.5%) were effective, 2 (7.7%) effective, 1 (3.8%) ineffective, and the total effective rate was 96.2% 2 cases (9.1%), 7 cases (31.8%) were ineffective and the total effective rate was 68.2%. The total effective rate of treatment group was significantly higher than that of control group (χ2 = 6.71, P <0.05) . Before and after treatment in both groups to detect blood, urine and liver and kidney function were normal, found no serious side effects. Conclusion Montelukast combined with budesonide in children with bronchial asthma, significant effect, can well control the recurrence of asthma and reduce the pain of children, is worthy of clinical promotion.