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本文对39例CML患者周围血淋巴细胞姐妹染色单体互换(SCE)率进行了观察,发现未治的慢性期患者SCE率显著降低,维持缓解期服用马利兰者SCE率高于未服药者,急变期SCE率显著增高。
In this paper, 39 cases of CML patients with peripheral blood lymphocytes sister chromatid exchange rate (SCE) was observed and found that untreated patients with chronic SCE significantly decreased the rate of sustained remission of malaran SCE rate was higher than those without medication, SCE rate was significantly increased in blast crisis.