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肾脏和高血压有极为密切的关系,无论原发性高血压还是继发性高血压,在发病机理上和肾脏的水盐代谢有关。肾脏的内分泌激素肾素(肾素、血管紧张素-醛固酮系统)、前列腺素和激肽等对血压调节均有重要作用。晚近对肾脏在调节血压和体液容量中的作用进行了大量研究,并不断分离出来源于肾脏的血管活性物质,对高血压的研究已取得了重大进展。目前人们不仅对肾实质和肾血管病变引起的高血压已有较深刻地了解。随着肾脏病变治疗的深入,以及新降压药物的问世,肾性高血压的预后也有了很大改观。为了交流这方面的经验,本刊特邀请省内外有关专家进行笔谈,供临床医务人员参考。
Kidney and hypertension are extremely closely related, regardless of whether the primary hypertension or secondary hypertension in the pathogenesis and kidney water and salt metabolism. Kidney endocrine hormone renin (renin, angiotensin-aldosterone system), prostaglandins and kinins and other blood pressure regulation have an important role. Numerous studies have recently been conducted on the role of the kidney in regulating blood pressure and fluid volume, and the continuous isolation of vasoactive substances derived from the kidneys has made significant advances in the study of hypertension. At present, people not only have a deeper understanding of the renal hypertension and renal hypertension caused by hypertension. With the further treatment of renal disease, and the advent of new antihypertensive drugs, the prognosis of renal hypertension has also been greatly improved. In order to exchange experience in this area, we also invited relevant experts from both inside and outside the province to have written speeches for clinical and medical staff’s reference.