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目的探讨胃肠动力药莫沙必利分散片与微生态制剂双歧杆菌乳杆菌三联活菌片(金双歧)联合治疗便秘型肠易激综合征(IBS)的临床疗效及护理方法。方法 58例便秘型IBS患者随机分为联合治疗组(31例)和对照组(27例)。联合治疗组给予莫沙必利分散片联合金双歧口服,对照组给予莫沙必利分散片联合谷维素片口服,两组均配合积极合理的护理措施,比较两组治疗效果。结果治疗8周后,联合治疗组总有效率为87.10%,明显高于对照组的62.96%,差异具有统计学意义(P<0.05)。两组治疗过程中随访观察,未见不良反应,治疗后复查血、尿常规及肝肾功未见异常。两组患者均按照要求及疗程服药,依从性较好。联合治疗组患者满意度为90.32%,明显高于对照组的66.67%,差异具有统计学意义(P<0.05)。结论莫沙必利联合金双歧治疗便秘型IBS能明显改善便秘症状,同时予以积极合理的护理措施有助于促进病情好转,提高患者治疗依从性及满意度,改善生活质量。
Objective To investigate the clinical efficacy and nursing of combined treatment of gastrointestinal motility drug mosapride dispersible tablets and probiotics probiotics bifidobacterium triple conjugate viable tablets (Jinshuangqi) in the treatment of constipation-induced irritable bowel syndrome (IBS). Methods 58 patients with constipation type IBS were randomly divided into combined treatment group (31 cases) and control group (27 cases). The combined treatment group was given mosapride dispersible tablets combined with Jinshuangqi orally, and the control group was given mosapride dispersible tablets combined with oryzanol tablets. Both groups were treated with positive and reasonable nursing measures, and the therapeutic effects were compared between the two groups. Results After 8 weeks of treatment, the total effective rate was 87.10% in the combination therapy group, which was significantly higher than that in the control group (62.96%). The difference was statistically significant (P <0.05). The two groups were followed up during the treatment, no adverse reactions, after treatment, review of blood, urine and liver and kidney function no abnormalities. Two groups of patients according to the requirements and medication medication, compliance is better. The satisfaction of patients in combination therapy group was 90.32%, which was significantly higher than 66.67% in control group, the difference was statistically significant (P <0.05). Conclusion Combined treatment of mosapride and Jinshuangqi can significantly improve the symptoms of constipation. At the same time, taking positive and reasonable nursing measures can help to improve the condition, improve the treatment compliance and satisfaction, and improve the quality of life.