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置放宫内节育器(IUD)共84例。其中置放金属单环21例,置硅—CuV型环24例,置含药(消炎痛)活性单粗165环39例,于卵泡期测定其血清中生殖激素水平,并与同期同等条件而未放器21例作对照。比较结果表明:置放IUD三组的妇女同正常未放器妇女其生殖激素FSH、LH、PRL、E2、P测定值均在卵泡期正常值范围。提示:IUD对性生殖轴功能影响不明显。但三组放器妇女其生殖激素FSH、PRL均明显高于对照组(P<0.01,P<0.001),而孕酮(P)显著降低P<0.001。提示:IUD与激素含量的变化有关,而卵泡期基础激素水平最终对黄体功能的影响值得进一步研究。
Place IUD a total of 84 cases. Among them, 21 cases were placed with single metal ring, 24 cases with Si-CuV ring and 39 cases with 165 single-ring active drugs (indomethacin). Serum levels of reproductive hormones were determined during follicular phase, 21 untreated control. The results showed that: women with IUD three groups of women with normal vaginal discharge reproductive hormones FSH, LH, PRL, E2, P measured in the normal range of follicular phase. Tip: IUD sexual reproductive axis function is not obvious. However, the FSH and PRL of reproductive hormones were significantly higher in the three groups of women than those in the control group (P <0.01, P <0.001), while the levels of progesterone (P) were significantly lower than those in the control group (P <0.001). Tip: IUD and hormone content changes, and the basic level of follicular basal hormone on the corpus luteum function deserves further study.