内镜黏膜切除术和剥离术治疗大肠早癌及癌前病变临床对比分析

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目的:探讨内镜黏膜切除术和黏膜下剥离术治疗大肠早癌及癌前病变的临床分析。方法:选择本院在2014年5月-2015年2月收治的42例患者,将其按照手术方式的不同分为观察组和对照组各21例,观察组实施内镜黏膜下剥离术治疗,对照组患者采取内镜黏膜切除术治疗,对比两组患者的手术时间、住院时间、完整切除率以及并发症发生率。结果:观察组平均手术时间为(84.62±19.65)min,平均住院时间为(5.47±1.67)d,并发症发生率为4.76%,其完整切除率为95.24%;对照组平均手术时间为(267.45±34.54)min,平均住院时间为(14.12±3.63)d,并发症发生率为42.86%,其完整切除率为66.67%。两组患者平均手术时间及住院时间、并发症发生率和完整切除率比较,差异有统计学意义(P<0.05)。结论:相较于内镜黏膜切除术,内镜黏膜下剥离术治疗大肠早癌及癌前病变的临床疗效更为显著,患者的肿瘤完整切除率较高,并发症少,且手术时间与住院时间也明显较短。 Objective: To investigate the clinical analysis of endoscopic mucosal resection and submucosal dissection in the treatment of colorectal cancer and precancerous lesions. Methods: Forty-two patients admitted to our hospital from May 2014 to February 2015 were divided into observation group (21 cases) and control group (21 cases) according to different surgical methods. The observation group received endoscopic submucosal dissection Patients in the control group were treated with endoscopic mucosal resection. The operation time, hospitalization time, complete resection rate and complication rate were compared between the two groups. Results: The average operation time in the observation group was (84.62 ± 19.65) min, the average hospitalization time was (5.47 ± 1.67) days, the complication rate was 4.76%, and the complete resection rate was 95.24%. The average operation time in the control group was (267.45) ± 34.54) min, the average length of hospital stay was (14.12 ± 3.63) days. The complication rate was 42.86%. The complete resection rate was 66.67%. The average operation time, hospital stay time, complication rate and complete resection rate of the two groups were significantly different (P <0.05). Conclusion: Compared with endoscopic mucosal resection, endoscopic submucosal dissection in the treatment of colorectal cancer and precancerous lesions of the clinical effect is more significant, the complete tumor resection rate in patients with high, fewer complications, and operative time and hospitalization Time is also significantly shorter.
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