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目的 观察康莱特注射液胸腔内注射治疗恶性胸腔积液的疗效。方法 将 6 0例恶性胸腔积液患者分为治疗组和对照组 ,采用胸腔闭式引流方法和胸腔内注射康莱特注射液或顺铂进行治疗。结果 治疗组 (CR +PR)为 86 .6 7% ,毒副反应率为 0～ 13.33% ;对照组分别为 56 .6 7%和 6 .6 7～ 4 0 .0 0 %。两组间差异有显著性 (P<0 .0 0 5)。结论 胸腔闭式引流方法配合康莱特注射液腔内注射治疗恶性胸腔积液有效率高且毒副反应轻 ,是一种值得推广的疗法
Objective To observe the curative effect of Kanglaite injection in treatment of malignant pleural effusion. Methods Sixty patients with malignant pleural effusion were divided into treatment group and control group. The patients were treated by closed thoracic drainage and intrapleural injection of Kanglaite injection or cisplatin. Results The treatment group (CR + PR) was 86.67%, the toxicity rate was 0 ~ 13.33%, while the control group was 56.67% and 6.76 ~ 400.0% respectively. The difference between the two groups was significant (P <0.05). Conclusions Thoracic closed drainage combined with KLT injection of malignant pleural effusion with high efficiency and light toxicity is an acceptable therapy