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氢化可的松在氯仿－水体系中分配系数的公式指出，用氢化可的松在两相中的溶解度可以预测其分配系数，通过实验分别研究了乙醇的浓度对氢化可的松在氯仿和水中溶解度及在两相中分配系数的影响。实验结果表明，乙醇的浓度与氢化可的松在水中的溶解度呈线性关系：与氢化可的松在氯仿中的溶解度呈指数关系；与氢化可的松在氯仿－水体系中的分配系数呈抛物线关系。此结果与理论预测存在偏差，这是由于乙醇在氯仿－水体系中分配系数很小，对氢化可的松在系统的平衡有较大影响造成的。综合以上因素，以及考虑到产量和生产成本等指标，证实了生产工艺中确定的乙醇浓度为水相体积的５％是合理的，为进一步回收乙醇提供了实验和理论基础。
The formula for the partition coefficient of hydrocortisone in a chloroform-water system indicates that the partition coefficient can be predicted by the solubility of hydrocortisone in the two phases. The concentration of ethanol on hydrocortisone in chloroform and water Solubility and Effect of Partition Coefficients in Two Phases. The experimental results show that the ethanol concentration has a linear relationship with the solubility of hydrocortisone in water: the solubility of hydrocortisone in chloroform is exponential; the partition coefficient of hydrocortisone in chloroform-water system is parabolic relationship. This result is biased against the theoretical predictions due to the small partition coefficient of ethanol in the chloroform-water system and the greater impact on system equilibrium of hydrocortisone. Combining the above factors, taking into account the production and production costs and other indicators, confirmed that the production process to determine the ethanol concentration of 5% of the volume of the water phase is reasonable, for further recovery of ethanol provides the experimental and theoretical basis.