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目的:探讨有创机械通气对突发致死性哮喘(SFA)治疗效果的影响。方法:回顾性分析2001年1月至2011年12月广东省梅州市丰顺县人民医院收治的42例SFA患者的临床资料,根据治疗方式不同分非机械通气组(27例)和机械通气组(15例),比较两组患者治疗后血气变化及症状缓解情况。结果:非机械通气组患者症状缓解平均时间为(90±20)min;机械通气组患者平均上机时间为(6±2)h。非机械通气组患者血气改善较机械通气组快(P<0.05)。结论:迅速有效地应用支气管扩张剂,对SFA具有较好疗效,而机械通气可则能延长血气改善和症状缓解所需时间。
Objective: To investigate the effect of invasive mechanical ventilation on the treatment of sudden fatal asthma (SFA). Methods: The clinical data of 42 SFA patients admitted to Fengshun County People’s Hospital, Meizhou City, Guangdong Province from January 2001 to December 2011 were retrospectively analyzed. According to the different treatment methods, the patients in non-mechanical ventilation group (27 cases) and mechanical ventilation group (15 cases). The blood gas changes and symptom relief were compared between the two groups after treatment. Results: The mean time to symptom relief was (90 ± 20) min in non-mechanical ventilation group and 6 ± 2 h in mechanical ventilation group. Patients with non-mechanical ventilation improved blood gas faster than the mechanical ventilation group (P <0.05). Conclusion: The rapid and effective use of bronchodilators has a good effect on SFA, while mechanical ventilation can prolong the time needed for improvement of blood gas and symptom relief.