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Neurons and glial cells,particularly astrocytes,are the two main cell populations in the central nervous system.While it is established that brain functions primarily rely on neuronal activity,an active contribution of astrocytes to information processing is only starting to be considered.There is growing evidence that astrocytes,as part of the tripartite synapse,participate in this challenge by receiving and integrating neuronal signals and,in turn,by sending signals that target neurons[1].