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目的评价依诺沙星注射液治疗呼吸系统感染和泌尿系统感染的有效性和安全性。方法用随机单盲对照试验设计,试验组依依诺沙星注射液:200mg,iV,gtt,bid,对照组予以左氧氟沙星注射液:200mg,iv,gtt,bid,2组疗程均为7￣14天。结果试验组病例为34例,对照组评价病例为36例。试验组临床总有效率和痊愈率分别为94.1%和64.7%;对照组临床总有效率和痊愈率分别为91.6%和66.6%。试验组和对照组药物不良发生率分别为10%(3/34)和33.3%(12/36)。2组比较除不良反应发生率差异有显著意义外,其余均无显著意义(P>0.05)。结论依诺沙星注射液治疗呼吸系统和泌尿系统急性细菌性感染疗效确切,使用安全、方便。
Objective To evaluate the efficacy and safety of enoxacin injection in the treatment of respiratory infections and urinary tract infections. Methods Randomized single-blind control trial design, the experimental group enoxacin injection: 200mg, iV, gtt, bid, the control group was levofloxacin injection: 200mg, iv, gtt, bid, the two courses were 7 to 14 days . Results The experimental group of 34 cases, the control group of 36 cases evaluated. The total clinical effective rate and cure rate in the experimental group were 94.1% and 64.7%, respectively. The total effective rate and cure rate in the control group were 91.6% and 66.6%, respectively. The incidence of adverse drug reactions in the experimental and control groups was 10% (3/34) and 33.3% (12/36), respectively. There was no significant difference between the two groups except for the difference in incidence of adverse reactions (P> 0.05). Conclusion Enoxacin injection is effective in treating acute bacterial infections of the respiratory system and urinary system. It is safe and convenient to use.