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甲状腺功能低下症对于心脏有多种功能上和病理学上的影响,包括间质纤维化样变和水肿的形成、心包液渗出、心肌肥大、静止期心输出量减少,以及减少钙的摄取率和依赖钙的三磷酸腺苷的水解作用。此外,甲状腺功能低下症具有体内总钠量增加及偶有其他电解质紊乱的特征。心房利钠尿肽(ANP)最近认识到是一种由心房释放的激素,可引起明显的钠尿和利尿,从而降低动脉压和肾酵素—血管收
Hypothyroidism has a variety of functional and pathological effects on the heart, including the formation of interstitial fibrosis and edema, pericardial effusion, cardiac hypertrophy, reduced quiescent cardiac output, and reduced calcium uptake Rate and calcium-dependent adenosine triphosphate hydrolysis. In addition, hypothyroidism has the feature of increased total body sodium and occasionally other electrolyte disturbances. Atrial natriuretic peptide (ANP) has recently been recognized as a hormone released by the atrium that causes pronounced natriuresis and diuresis, thereby reducing arterial pressure and renal enzyme-angiogenesis