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目的:观察应用喜炎平注射液与蒙脱石散联合治疗小儿轮状病毒肠炎的临床疗效。方法:将83例轮状病毒肠炎患儿采用抽签法随机分成对照组44例和实验组39例,2组均采用常规输液等综合性对症处理,对照组加用利巴韦林注射液,实验组加用喜炎平注射液和蒙脱石散联合治疗,2组均治疗3天,观察3周。比较2组的临床疗效。结果:实验组患儿主要症状消退时间及住院时间均短于对照组,差异均有显著性意义(P<0.05)。治疗3天后,总有效率实验组为89.7%,对照组为65.9%,2组比较,差异有显著性意义(P<0.05)。观察1周、2周、3周,2组的大便轮状病毒转阴率分别比较,差异均有显著性意义(P<0.05)。结论:喜炎平注射液与蒙脱石散联合应用于小儿轮状病毒肠炎的临床治疗,能明显缩短病程,疗效显著。
Objective: To observe the clinical effect of Xiyanping injection combined with montmorillonite powder in treating rotavirus enteritis in children. Methods: Eighty-three children with rotavirus enteritis were randomly divided into control group (n = 44) and experimental group (n = 39). The two groups were treated with routine symptomatic infusion. The control group was treated with ribavirin injection, Group plus Xiyanping injection and montmorillonite combination therapy, two groups were treated for 3 days, observed for 3 weeks. Compare the clinical efficacy of the two groups. Results: The main symptoms of children in experimental group were shorter than those in control group (P <0.05). After 3 days of treatment, the total effective rate was 89.7% in the experimental group and 65.9% in the control group. There was significant difference between the two groups (P <0.05). Observed at 1 week, 2 weeks, 3 weeks, two groups of stool rotavirus negative rates were compared, the differences were significant (P <0.05). Conclusion: Xiyanping injection combined with montmorillonite powder in clinical treatment of pediatric rotavirus enteritis, can significantly shorten the course of the disease, the effect is significant.