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钙粘蛋白E(E-cad)是分子量为120KDa的细胞粘附跨膜糖蛋白,E-cad的表达与肿瘤浸润转移呈负相关。本文概述E-cad的生物学特性、功能调控、检测及与泌尿系肿瘤生物学行为的关系。
Cadherin E (E-cad) is a cell adhesion transmembrane glycoprotein with a molecular weight of 120 KDa. The expression of E-cad is negatively correlated with tumor invasion and metastasis. This article summarizes the biological characteristics of E-cad, function regulation, detection and the relationship with the biological behavior of urinary tumors.