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目的观察替吉奥胶囊联合伊立替康治疗晚期结直肠癌的治疗效果。方法选取80例晚期直肠癌患者,随机分为两组。观察组联合静脉滴注替吉奥胶囊和伊立替康;对照组使用奥沙利铂静脉滴注。两组均使用4个疗程后检验临床效果。结果观察组的总有效率比对照组的明显要高(P<0.05),毒性反应上观察组要优于对照组,但是没有统计学差异(P>0.05)。结论替吉奥胶囊联合伊立替康治疗晚期结直肠癌的临床效果要优于奥沙利铂滴注,毒性反应较轻,可以提高患者的生存质量和生存率。
Objective To observe the therapeutic effect of TIGO capsules combined with irinotecan in the treatment of advanced colorectal cancer. Methods Eighty patients with advanced rectal cancer were selected and randomly divided into two groups. The observation group was treated with intravenous infusion of tioguan capsule and irinotecan, while the control group was given oxaliplatin intravenous drip. After two courses of treatment were used to test the clinical effect. Results The total effective rate of the observation group was significantly higher than that of the control group (P <0.05). The toxicity of the observation group was superior to that of the control group, but there was no significant difference (P> 0.05). Conclusion The efficacy of tigeo capsule combined with irinotecan in the treatment of advanced colorectal cancer is better than that of oxaliplatin instillation. The toxic reaction is mild, which can improve the quality of life and survival rate of patients.