Tetrahydroxy Stilbene Glucoside Ameliorates Cognitive Impairments and Pathology in APP/PS1 Transgeni

• 作 者: Dan GAO Chen CHEN Rui HUANG Cui-cui YANG Bei-bei MLAO Lin LI Lan ZHANG
• 机 构: DepartmentofPharmacy
• 出 处: 当代医学科学(英文)
• 发表日期: 2021年2期
• 关键词: tetrahydroxy stilbene glucoside APP/PS1 transgenic mice cognitive impairments am
• 基金项目: supported by grants from the National Natural Science Foundation of China(No.81803537),the"Major New Drug Creation"of Major Science and Technology Project(No.2015ZX09101-016),Capital Science and Techn

Cognitive impairment is the main clinical manifestation of Alzheimers disease(AD),and amyloid-β(AB)deposition and senile plaques are the characteristic neuropathological hallmarks in AD brains.This study aimed to explore the effect and mechanism of tetr