附睾乳头状囊腺瘤1例报道及文献复习

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目的 探讨附睾乳头状囊腺瘤的临床病理学特征、免疫表型、诊断及鉴别诊断,提高对附睾乳头状囊腺瘤的认识.方法 对西藏自治区人民医院收治的这1例附睾乳头状囊腺瘤的临床资料、影像资料、大体形态、组织结构、免疫组化染色结果进行观察和分析,并结合文献复习.结果 临床检查显示阴囊处无痛性肿块,B超示左侧附睾体可探及中等低回声结节,考虑炎性病变;大体灰红囊性,大小4cm×3cm×2.5cm,包膜完整,切面呈囊性,囊内为暗红色胶样物,边界清;镜下扩张的导管和小囊肿被覆柱状上皮,以纤维血管间质为轴心的乳头状腺样结构,囊腔内可见乳头,囊内见嗜伊红样物质;免疫组织化学标记物染色结果示AE/AE 3(+),EMA(+),Ki-67(index1%),P53(-),MC(-),Calretinin(-),CD 10(-).结论 附睾乳头状囊腺瘤罕见,可伴有VH L综合征,确诊主要靠病理形态学特征结合免疫组化表型综合判断.
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