论文部分内容阅读
热毒清(原名抗炎6号)系我校附属同济医院用四味清热解毒中药制成的静脉注射液,具有抑菌、抗炎、解毒、退热、增强免疫功能及稳定溶酶体膜、保护线粒体H~+-ATP合酶等多方面的作用,其多相药理作用可能与保护生物膜活性有关。本实验研究热毒清对内毒素所致家兔红细胞膜Na~+,K~+-ATP酶活性损害作用的影响,以探讨热毒清治疗疾病的机理。 一、材料和方法 1.动物、健康日本大耳白兔24只,体重2～2.5 kg, 雌雄不拘,随机分为4组,每组6只。①正
Hot Duqing (formerly known as Anti-inflammatory No.6) is an intravenous injection made from the four flavors of Qingrejiedu traditional Chinese medicine in the Tongji Hospital Affiliated to our school. It has antibacterial, anti-inflammatory, detoxification, antipyretic, immune enhancement, and stable lysosomal membranes. The protection of mitochondrial H~+-ATP synthase and many other aspects of its multi-phase pharmacological effects may be related to the protection of biofilm activity. This experiment was conducted to study the effect of Reduqing on the damage of Na~+, K~+-ATPase activity of rabbit erythrocyte membrane induced by endotoxin, in order to investigate the mechanism of the treatment of the disease by the hot poisonous toxin. First, materials and methods 1. Animals, healthy Japanese white rabbits 24, weighing 2 to 2.5 kg, male or female, are randomly divided into 4 groups, 6 in each group. 1 positive