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目的:探讨中西医结合治疗儿童急性支气管炎临床疗效及其安全性评价,为临床诊断治疗提供参考。方法:将本组136例急性支气管炎患儿按照随机数字表法分为对照组(n=68)和观察组(n=68);对照组采用西医对症治疗,观察组在对照组治疗基础上服用小青龙汤;两组治疗均以7 d为1个疗程。2个疗程后统计疗效,观察两组患儿治疗前后咳嗽、发热、咳痰评分变化及不良反应发情况。结果:治疗组总有效率(94.12%)显著高于对照组(80.88%),且差异有统计学意义(P<0.05);两组患儿治疗后咳嗽、发热、咳痰评分显著低于治疗前,且差异有统计学意义(P<0.05);观察组治疗后咳嗽、发热、咳痰评分显著低于对照组,且差异有统计学意义(P<0.05)。两组患儿在治疗过程中均无明显不良反应发生,用药安全有效。结论:小青龙汤联合西医对症治疗儿童急性支气管炎疗效显著,且用药安全可靠,具有重要的研究价值。
Objective: To explore the clinical efficacy and safety evaluation of integrated traditional Chinese and western medicine in the treatment of childhood acute bronchitis, and to provide reference for clinical diagnosis and treatment. Methods: 136 children with acute bronchitis were randomly divided into control group (n = 68) and observation group (n = 68) according to random number table. The control group was treated with western medicine. The observation group was treated with the control group Taking Xiaoqinglong Decoction; both treatment are 7d for a course of treatment. After 2 courses of treatment, the curative effect of cough, fever, sputum score and adverse reactions were observed before and after treatment. Results: The total effective rate (94.12%) in the treatment group was significantly higher than that in the control group (80.88%), and the difference was statistically significant (P <0.05). The cough, fever and sputum score were significantly lower in the two groups after treatment (P <0.05). The scores of cough, fever and sputum in the observation group after treatment were significantly lower than those in the control group (P <0.05). Two groups of children in the course of treatment were no significant adverse reactions, safe and effective medication. Conclusion: Xiao Qing Long Decoction combined with western medicine treatment of children with acute bronchitis significant effect, and safe and reliable medication, has important research value.