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先天性唇瘘较少见,也称作唇凹或唇窦道,多位于下唇红中线两侧,极少位于上唇及口角。常与唇、腭裂同时存在,具有遗传史,又称为Vander Woude综合征。本病畸形较轻,仅唇部轻微异常和瘘口有无色粘液流出引起不适,但必须注意其伴随畸形和唇、腭裂较高的遗传发生率。 本组男5例,女3例。年龄6月～8岁。患儿出生后即被发现唇部瘘口,无自觉症状,常有粘液自瘘口流出。追问病史2例下唇瘘患儿父母均患唇腭裂及唇瘘,1例上唇瘘患儿母亲妊娠期服用苯海拉明、扑尔敏等药。 瘘口位于下唇红中线两侧呈对称性排列者5例,下唇红中线上单一瘘口1例,下唇皮肤中线旁瘘口1例,上唇人中皮肤瘘口1例。8例患儿均伴有其它畸形,其中伴发双侧完全性腭裂5例,单侧完全性腭裂1
Congenital lip fistula is less common, also known as lip concave or lip sinus, mostly in the lower lip red line on both sides, rarely located in the upper lip and mouth. Often with the lip, cleft palate exists at the same time, with a genetic history, also known as Vander Woude syndrome. The disease deformity lighter, only a slight abnormal lip and fistula have colorless mucus flow caused by discomfort, but must pay attention to its accompanying deformity and lip, cleft palate higher genetic incidence. The group of 5 males and 3 females. Aged 6 months to 8 years old. Children were found after birth lip fistula, no symptoms, often mucus from the fistula outflow. History of 2 cases asked the history of lower lip fistula parents were suffering from cleft lip and palate and lip fistula, 1 case of upper lip fistula mother taking diphenhydramine during pregnancy, chlorpheniramine and other drugs. Fistula in the middle of the lower lip red line on both sides of the symmetry arrangement in 5 cases, the lower lip red line in a single fistula in 1 case, lower lip midline fistula in 1 case, upper lip in the skin fistula in 1 case. 8 cases of children were accompanied by other deformities, including bilateral complete cleft palate in 5 cases, unilateral complete cleft palate 1