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目的观察叶酸联合水溶性维生素治疗高同型半胱氨酸(Homocysteine,Hcy)血症1周的干预作用。方法选取血浆Hcy增高患者60例,给予叶酸5 mg,3次/d,水溶性维生素340 mg静脉滴注,1次/d。于治疗前及治疗1周时抽空腹静脉血5 ml,检测血浆Hcy。结果治疗组血浆Hcy水平治疗前为(35.03±6.86)μmol/L,治疗后(25.57±5.14)μmol/L,治疗前后Hcy水平差异无统计学意义(P>0.05)。结论叶酸联合水溶性维生素治疗高同型半胱氨酸血症一周,Hcy水平有下降趋势,但治疗效果不明显。
Objective To observe the intervention effect of folic acid combined with water-soluble vitamins for one week of hyperhomocysteinemia. Methods Sixty patients with elevated plasma Hcy levels were given folic acid 5 mg three times a day, and water-soluble vitamins 340 mg intravenously once a day. Before treatment and 1 week after treatment, fasting venous blood was drawn 5 ml to detect plasma Hcy. Results The level of Hcy in the treatment group before treatment was (35.03 ± 6.86) μmol / L, and after treatment (25.57 ± 5.14) μmol / L, there was no significant difference in the level of Hcy before and after treatment (P> 0.05). Conclusion Folic acid combined with water-soluble vitamins treatment of homocysteinemia week, Hcy levels have a downward trend, but the treatment effect is not obvious.