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目的 观察血液系统恶性肿瘤血清肿瘤坏死因子α(TNF α)的变化及临床意义。方法 检测 40例血液系统恶性肿瘤患者血清TNF α的水平。结果 血液系统恶性肿瘤患者血TNF α水平与对照组相比明显升高。动态观察急性白血病不同病期TNF α的变化表明 :初治与未缓解及复发病人TNF α水平升高 ,缓解期下降。结论 TNF α是血液系统恶性肿瘤病情监测的一个有用指标
Objective To observe the changes and clinical significance of serum tumor necrosis factor α (TNF α) in hematological malignancies. Methods The serum levels of TNF α were detected in 40 patients with hematological malignancies. Results The level of blood TNFα in patients with hematological malignancy was significantly higher than that in the control group. Dynamic observation of the changes of TNF-α in different stages of acute leukemia indicated that the levels of TNF α were increased in the untreated and relapsed patients and decreased in remission. Conclusion TNF α is a useful indicator for monitoring the malignancy of hematological malignancies