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对36例多发性骨髓瘤(MM)患者骨髓涂片,行酸性磷酸酶(ACP)染色。结果发现MM组的骨髓浆细胞ACP积分明显高于对照组。MM组初诊时、缓解期和复发期46人次检测结果表明,在MM病程中ACP积分随病情变化而变化,缓解期的较初诊时降低,复发期的又复增高。这种变化有时较骨髓浆细胞比例的变化与病情的关系更为密切,揭示ACP积分可作为MM病情监测的指标。
Bone marrow smears from 36 patients with multiple myeloma (MM) were stained for acid phosphatase (ACP). The results showed that the ACP scores of bone marrow plasma cells in the MM group were significantly higher than those in the control group. The results of the 46 visits at the time of initial diagnosis, remission and relapse in the MM group showed that the ACP scores varied with the disease in the course of MM. The remission period was lower than the initial diagnosis, and the relapse period was increased again. This change is sometimes more closely related to changes in the proportion of bone marrow plasma cells and the condition, revealing that the ACP score can be used as an indicator of MM condition monitoring.