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目的:研究参麦注射液联合尿激酶静脉溶栓治疗急性前壁心肌梗死的临床疗效及其对患者心功能的影响。方法:将122例急性前壁心肌梗死患者随机分为观察组、对照组各61例,对照组患者采用尿激酶静脉溶栓治疗,观察组患者在对照组治疗基础上联合参麦注射液治疗,比较两组患者的临床疗效以及心功能情况。结果:观察组患者优良率(96.72%)显著高于对照组(78.69%),差异具有统计学意义(P<0.05);治疗后两组患者左心室舒张末内径、射血分数值均明显改善,且观察组患者改善情况显著优于对照组,差异具有统计学意义(P<0.05);两组患者治疗后Hcy水平均降低,cTnT水平均上升,且观察组患者Hcy、cTnT指标改善情况显著优于对照组,差异具有统计学意义(P<0.05)。结论:在尿激酶静脉溶栓治疗基础上联合参麦注射液治疗急性前壁心肌梗死患者临床疗效显著,可有效改善患者心功能、心肌酶学指标,值得临床推广应用。
Objective: To study the clinical efficacy of Shenmai injection combined with urokinase intravenous thrombolysis in the treatment of acute anterior myocardial infarction and its effect on cardiac function. Methods: A total of 122 patients with acute anterior myocardial infarction were randomly divided into observation group and control group with 61 cases in each group. Patients in the control group were treated with intravenous thrombolytic therapy of urokinase. Patients in observation group were treated with Shenmai injection on the basis of the control group, The clinical efficacy and cardiac function of the two groups were compared. Results: The excellent and good rate (96.72%) in the observation group was significantly higher than that in the control group (78.69%), the difference was statistically significant (P <0.05); after treatment, the left ventricular end-diastolic diameter and ejection fraction were significantly improved , And the improvement in observation group was significantly better than that in control group, the difference was statistically significant (P <0.05). The Hcy level and cTnT level of both groups decreased after treatment, and the improvement of Hcy and cTnT index in observation group was significant Better than the control group, the difference was statistically significant (P <0.05). Conclusion: The clinical efficacy of combined intravenous thrombolytic therapy and Shenmai injection in the treatment of patients with acute anterior myocardial infarction is significant, which can effectively improve the cardiac function and myocardial enzymological indexes of patients and is worthy of clinical application.