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目的:探讨以MRI诊断的不同程度早产儿脑室周围-脑室内出血(PV-IVH)的相关危险因素。方法:以MRI(T1WI-T2WI)和弥散加权成像诊断PV-IVH,并根据损伤程度进行分级。详细统计临床资料,进行单因素分析,对单因素分析有统计学意义的因素行PV-IVH的Logistic回归分析。回顾性分析天津医科大学第二医院2008年7月-2012年12月的PV-IVH患者相关危险因素。根据PV-IVH分级分为轻度和重度PV-IVH,并进行有序多分类Logistic回归分析。结果:男性、阴道分娩、产前母亲感染、高碳酸血症、低碳酸血症是早产儿PV-IVH的危险因素;男性、阴道分娩、双胎、高碳酸血症及循环功能障碍更易造成重度PV-IVH。结论:理解PV-IVH的危险因素有助于探索阻止发生早产儿神经系统异常的有效策略,围产期护理对提高早产儿质量极其重要。
Objective: To explore the related risk factors of periventricular-ventricular hemorrhage (PV-IVH) in preterm infants with different degrees diagnosed by MRI. Methods: PV-IVH was diagnosed by MRI (T1WI-T2WI) and diffusion-weighted imaging and graded according to the degree of injury. Detailed statistics of clinical data, univariate analysis, univariate analysis of statistically significant factors PV-IVH Logistic regression analysis. Retrospective analysis of the Second Hospital of Tianjin Medical University from July 2008 to December 2012 PV-IVH patients with risk factors. According to the classification of PV-IVH, mild and severe PV-IVH were divided into two groups. Logistic regression analysis was performed. Results: Male, vaginal delivery, prenatal maternal infection, hypercapnia, hypocapnia were risk factors for PV-IVH in preterm infants; men, vaginal delivery, twins, hypercapnia and circulatory dysfunction were more likely to cause severe PV-IVH. CONCLUSIONS: Understanding the risk factors for PV-IVH is useful in exploring effective strategies to prevent neurological abnormalities in preterm infants, and perinatal care is extremely important in improving the quality of preterm infants.