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目的：通过MRI及细胞图像分析仪，探讨原发性支气管肺癌MRI信号与DNA倍体的关系。材料与方法：23例原发性支气管肺癌患者，于术前2周，行Resonex0．38T磁共振成像（横断面SET1WI、GR、增强后SET1WI）。术后标本用ICM－100细胞图像分析仪，测定每例肺癌标本的DNA含量及SPF值。结果：T1加权平扫二倍体肿瘤信号强度比（病变／椎体）显著小于异倍体肿瘤的信号强度比。二倍体肿瘤的SPF值也显著小于异倍体肿瘤的SPF值。但MRI信号强度比不能反映肺癌的SPF值。结论：MRI信号强度在一定程度上可反映肿瘤细胞的倍体情况，即可间接地反映肿瘤细胞的生物学行为。
Objective: To investigate the relationship between MRI signal and DNA ploidy in primary bronchogenic carcinoma by MRI and cell image analyzer. Materials and Methods: Twenty-three patients with primary bronchogenic carcinoma underwent Resonex 0.38T magnetic resonance imaging (cross-sectional SET1WI, GR, and enhanced SET1WI) 2 weeks before surgery. The postoperative specimens were analyzed by ICM-100 cell image analyzer to determine the DNA content and SPF value of each specimen of lung cancer. RESULTS: The T1-weighted plain diploid tumor signal intensity ratio (lesion/vertebral body) was significantly smaller than that of aneuploid tumors. The SPF value of the diploid tumor was also significantly smaller than the SPF value of the aneuploid tumor. However, the MRI signal intensity ratio does not reflect the SPF value of lung cancer. Conclusion: MRI signal intensity can reflect the ploidy of tumor cells to a certain extent, which can reflect the biological behavior of tumor cells indirectly.