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目的:探讨在常规治疗基础上加用阿魏酸哌嗪对原发性肾病综合征(PN S)的效果。方法:将46例原发性肾病综合征患者随机分为对照组22例,应用激素等常规治疗;治疗组24例,在常规治疗基础上加用阿魏酸哌嗪。结果:治疗组与对照组治疗14 d相比,其血浆黏度、24 h尿蛋白定量、血肌酐均明显下降(P<0.05),血浆白蛋白较治疗前明显上升(P<0.05)。结论:在常规治疗基础上加用阿魏酸哌嗪治疗PN S是一种有效的方法。
Objective: To investigate the effect of adding ferulic acid piperazine on primary nephrotic syndrome (PN S) based on routine treatment. Methods: Forty-six patients with primary nephrotic syndrome were randomly divided into control group (n = 22) and conventional therapy with hormone. The treatment group (n = 24) was given routine treatment with piperazine ferulate. Results: Compared with the control group, the plasma viscosity, 24 h urinary protein and serum creatinine were significantly decreased (P <0.05) and plasma albumin significantly increased (P <0.05). Conclusion: The addition of piperazine ferulate to PNS is an effective method based on routine treatment.