论文部分内容阅读
二尖瓣脱垂(MVP)即使没有造成血流动力学损伤也可出现室性心律失常和心源性猝死(SCD),心室电不稳定的结构基础尚不明确。本研究回顾了“心脏注册研究”中650例SCD的年轻患者(≤40岁),重新复习了MVP为SCD唯一合并疾病的患者资料。共有43例MVP患者(26例女性,年龄在19~40岁,中位年龄32岁),占所有SCD 7%,女性的13%。在12例有心电图资料的患者中,10例(83%)在下壁导联出现T波倒置,而且均为右束支传导阻滞型(RBBB)室性心律失常,70%有双瓣尖受累。组织学检查发现所有患者在乳头肌水平均有左室纤维化表现,88%还出现在左室下壁基底部。将MVP患者分为合并复杂室性
Mitral valve prolapse (MVP) can occur even without causing hemodynamic damage to ventricular arrhythmias and sudden cardiac death (SCD), the structural basis of ventricular electrical instability is not yet clear. This study reviews 650 young patients (≤40 years) with SCD from the Heart Registry Study and revisits MVP as the only patient with SCD. A total of 43 MVP patients (26 women, aged 19-40 years and median age 32 years) accounted for 7% of all SCDs and 13% of women. Of the 12 patients with ECG data, 10 (83%) had T wave inversion in the inferior leads and were all right bundle branch block (RBBB) ventricular arrhythmias and 70% had double-lobe involvement . Histological examination revealed that all patients had LV fibrosis at papillary level, and 88% appeared at the base of the LV wall. The MVP patients were divided into complex complex sex